Orbitrap Exploris 240

Orbitrap Exploris 240 mass spectrometer is a Thermo Scientific™ quadrupole-Orbitrap™ mass spectrometer, which is based on proven hardware and instrument control software designs of the next-generation Thermo Scientific mass spectrometers and incorporates extensive customer and service engineer feedback.

The Orbitrap Exploris 240 mass spectrometer provides the performance and versatility needed to drive discovery and identification, and the quantitative precision and accuracy to confidently scale up for impact. Operational simplicity with intelligent acquisition of high-resolution accurate-mass data (HRAM) provides the fast path to high-quality results for users of all skill levels in a range of applications including small molecule, peptide, and intact protein analyses. Identifying small molecule unknowns, performing comprehensive characterization of complex biotherapeutics, and undertaking impactful proteomic research shouldn’t require you to work harder to find answers.

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Consistent Mass Accuracy

Ensure complete confidence in results with sub-ppm mass accuracy for at least five days provided by the Thermo Scientific™ EASY-IC™ (internal calibration) source and a simple, single external calibration across the entire mass range of m/z 40–6,000.

Excellent Mass Accuracy and Resolution Combine for Data Certainty

High-resolving power enables you to differentiate between matrix interferences and analytes of interest. Orbitrap mass analyzer resolution up to 240,000 at m/z 200. Scan Rate up to 22 Hz at resolution setting at 15,000.

Accurate, Optimization-Free Quantitation

From small-molecule unknown identification to protein, peptide, and biotherapeutic applications, combining excellent mass accuracy and resolution with the ability to perform quantitation using full scan or targeted data acquisition modes, you can be sure of obtaining the highest possible sensitivity and dynamic range regardless of sample matrix complexity.

Software

Powerful software tools connect small-molecule unknown identification and characterization to screening and quantitation. Once you have acquired comprehensive, high-quality MS and MS2 data, our software ecosystem is designed to reduce the time to high-confidence insights.

• Streamline qualitative and quantitative data analysis using template-driven data processing
• Access world-leading mass spectral fragmentation libraries to identify compounds
• Seamlessly transfer knowledge from discovery to everyday testing
• When regulatory compliance is required, Chromeleon CDS software delivers productivity with MS quantitation and targeted screening capabilities

Benefits

• Premium quantitative and qualitative performance with the fast scanning High-Field Thermo Scientific™ Orbitrap™ mass analyzer
• Next-generation software with intuitive tuning, single-click calibration, drag-and-drop method setup, and pre-defined experiments
• Compatible with Thermo Scientific™ next generation ion sources including FAIMS Pro Duo interface
• Comprehensive, automated sample profiling with Thermo Scientific™ AcquireX™ data acquisition workflow
• Set up and forget with maximum mass accuracy provided, using built-in Thermo Scientific™ EASY-IC™ ion source internal reference mass
• Extended mass transmission and detection up to m/z 8,000 with the Thermo Scientific™ BioPharma option