Orbitrap IQ-X Tribrid


Orbitrap IQ-X Tribrid

Orbitrap IQ-X Tribrid mass spectrometer redefines small molecule identification and characterization by leveraging the proven and trusted Tribrid architecture with intelligent MSn acquisition using Real-Time Library Search to improve annotation and structural characterization of unknown analytes. Reveal complex chemical structures with ultimate confidence, ease, and experimental versatility. Built specifically for next-generation small-molecule analysis, the Thermo Scientific Orbitrap IQ-X Tribrid mass spectrometer helps you maintain the lead with comprehensive unknown identification workflows.


Features and benefits Orbitrap IQ-X Tribrid Mass Spectrometer

  • A combination of the best quadrupole, linear ion trap and Thermo Scientific Orbitrap mass analyzer technologies
  • Automated, remote and hands-free calibration with the Auto-Ready ion source
  • Real-Time Library Search provides higher confidence for small molecule analysis
  • Expanded Thermo Scientific AcquireX workflow capabilities produce easy
  • Expectational mass accuracy to <1 ppm with Thermo Scientific EASY-IC ion source
  • Flexible fragmentation techniques for structural determination of lipids, metabolites and other small molecules utilizing Collison induced association (CID), Higher-energy collisional dissociation (HCD) and optional Ultraviolet Photodissociation (UVPD)
  • Improve unknown analysis with ultra high 500.000 resolution at m/z 200 and fine isotope detection with optional Thermo Scientific 1.000.000 resolution at m/z 200.
  • Thermo Scientific OptaMax NG ion source for enhanced usability and robustness with a redesigned HESI sprayer and built-in APCI assembly
  • Expansive collection of application specific, small molecule one-click method templates for metabolomics, lipidomics, metabolite ID, impurities, extractables and leachables, and more

Optional Hardware

  • Thermo Scientific UVPD ion source – includes a Class 1, 213 nm laser system with 2.5 kHz delivering >1.2 uJ per pulse
  • Thermo Scientific 1M resolution
  • Thermo Scientific FAIMS Pro Duo interface – optimized performance for 100 nL/min to 1 mL/min 

Performance Characteristics

  • Mass range – full mas range 50-2000 m/z
  • Orbitrap mass analyzer resolution –
  • Acquisition rate – Orbitrap MSn up to 40 Hz
  • Mass accuracy – <3 ppm RMS using external calibration and <1 ppm using internal calibration
  • MS ESI ion trap sensitivity 
  • Dynamic range – >5000 within a single MS acquisition
  • Multiplexing using the ion-routing multipole – up to 10 precursors per acquisition
  • Polarity switching
  • Analog inputs – channel 1( 0-10 V) and channel 2 (0-2 V)


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