Orbitrap Q Exactive Plus


Orbitrap Q Exactive Plus

Orbitrap Q Exactive Plus benchtop LC-HRMS combines high-performance quadrupole precursor selection with high-resolution (up to 280,000 FWHM) accurate-mass (HR/AM) Orbitrap™ detection to deliver high performance and tremendous versatility. It takes Quanfirmation™ to a new level, making it possible to characterize, quantify, and confirm in a single analysis with a  single instrument. The superior quality of data provides ultimate confidence for a wide range of qualitative and quantitative applications. Its high scan speed and spectral multiplexing capabilities make it fully compatible with UHPLC, nanoLC, PaperSpray and fast chromatography techniques, ramping productivity to a new level.

Technical enhancements to the original Orbitrap Q Exactive instrument maximize performance and reliability for large- and small-molecule applications. Advanced quadrupole technology (AQT) improves precursor selection and transmission for more-accurate quantitation of low-abundance analytes in complex matrices. Sophisticated data-independent acquisition (DIA) and parallel reaction monitoring (PRM) deliver reproducible quantitation with complete qualitative confidence. An advanced active beam guide (AABG) reduces noise and extends maintenance intervals. HR/AM and full-scan capabilities capture all sample data, all of the time, enabling retrospective data analysis without need to re-run samples. The key applications of Orbitrap Q Exactive Plus is equally useful for untargeted metabolomics, proteomics, lipidomics, intact antibody characterization and bioanalysis for biopharmaceuticals, clinical research, halal analysis of gelatin, drug of abuse, sports doping such as human and horse urine quantitation, environmental analysis such as screening of contaminants and quantitations, food safety analysis and many more.

The Thermo Scientific™ Q Exactive™ Plus LC-HRMS is the ideal quan/qual screening platform, with specificity that far exceeds triple quadrupole, Q-TOF, or Q-Trap levels. Whether screening and quantifying antibiotics, pesticides or hormones, its data-dependent™, full-scan MS/MS capabilities, superior 280,000 resolution and mass accuracy ensure the highest possible confidence in every ID. The Thermo Scientific™ Q Exactive™ Plus LC-HRMS takes quantitative analyses to another level, providing the strength of PRM with a level of confidence only possible with high-resolution, accurate-mass Orbitrap™ technology.

The ability to routinely and confidently identify, quantify, and confirm in a single analysis using a single mass spectrometer. The Thermo Scientific™ Q Exactive™ Plus takes Quanfirmation to a new level with increased performance meeting applied markets requirements. In short, the versatility and high data quality of the Q Exactive™ Plus™ LC-HRMS system make it a valuable addition to any modern laboratory.

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