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There are circumstances when even the highest resolution is not enough. For certain isotope systems (e.g. Rb-Sr), there are isobaric interferences that cannot be overcome with ICP-MS technology. Neoma MS/MS MC-ICP-MS provides the solution. The unique MS/MS technology in Neoma MS/MS MC-ICP MS allows you to separate isobaric interferences by reaction with gas in a dedicated collision/reaction cell. Neoma MS/MS MC-ICP-MS provides exceptional versatility allowing the largest number of isotope systems to be analyzed through its unique pre-cell mass filter technology. By removing matrix elements before reaction, Neoma MS/MS MC-ICP-MS paves the way in the field of laser ablation MC-ICP-MS and beyond.
For scientists who are familiar with triple quadrupole ICP-MS/MS technology, Neoma MS/MS MC-ICP-MS represents a technological innovation in terms of precision and accuracy. Using the same principles of filter, reaction, and separation pioneered by triple quadrupole ICP-MS/MS, the Neoma MS/MS MC-ICP-MS enables effective removal of isobaric interferences with the added benefit of simultaneous isotope analysis, thus enabling the highest precision and accuracy of your isotope ratios.
You can analyze samples by utilizing standard MC-ICP-MS or MS/MS technology.
With the Neoma MS/MS MC-ICP-MS, you have an advanced MC-ICP-MS that can be used for high-precision isotope analysis without the use of dedicated collision/reaction cell technology. The “full transmission mode” provides the same accuracy, sensitivity, and precision that you get with a conventional Neoma MC-ICP-MS. In addition, you can use the pre-cell mass filter to remove matrix elements and improve sensitivity.
For isotope systems with significant isobaric interference, MS/MS technology can be enabled. Therein, Neoma MS/MS MC-ICP-MS differentiates itself from other CRC-ICP-MS technologies with the pre-cell mass filter. The patented technology removes matrix elements that may act as a cause of secondary reactions in CRC, which in some cases can amplify (rather than eliminate) isobaric interference.
Trusted Neoma MS/MS MC-ICP-MS Technology
The latest technology, built from the robust Neoma MC-ICP-MS platform, gives you all the benefits of the Neoma MC-ICP-MS, but with the option of MS/MS functionality to eliminate isobaric interference.
The new relay system of the Neoma MS/MS MC-ICP-MS has doubled the dynamic range of all ion current amplifiers, so you can measure with greater precision.
Scattered ions from major isotopes can bias the ratio measured on adjacent minor isotopes. Retarding Potential Quadrupole (RPQ) improves sensitivity by an order of magnitude. The Neoma MC-ICP-MS can be configured with two RPQ lenses for simultaneous analysis of 234U and 236U. The pre-cell mass filter of the Neoma MS/MS MC-ICP-MS suppresses matrix elements, increasing sensitivity to <50 ppb.
Equipped with 24 ion current amplifiers mounted in a double-shielded, evacuated and thermostatted case with a temperature stability of 0.01˚C/h, which ensures initial and gain stability. A software-controlled relay matrix connects any amplifier to any Faraday cup, meeting any analytical measurement requirements.
At the heart of the Neoma MS/MS MC-ICP-MS is an enhanced variable multicollector detector array with 11 Faraday cup detectors. This highly reliable mechanism brings all Faraday cups into precise alignment with ion beams of different dispersions. This ensures the flexibility to cover isotope applications from Li to U, in low or high resolution, and without compromising the original dispersion of the mass analyzer.

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