ISQ EC Single Qadrupole Mass Spectrometer


ISQ EC Single Qadrupole Mass Spectrometer

ISQ EC mass spectrometer is a sensitive analytical instrument that answers the questions “what is there” and “how much is present” for an incredibly wide range of analytical samples, which involves the production and subsequent separation and identification of charged species. Mass spectrometer is an instrument designed to separate gas phase ions according to their m/z (mass to charge ratio) value.

A single quadrupole mass spectrometer contains one quadrupole mass analyzer. The quadrupole mass analyzer acts as a mass filter, allowing users to select either a specific m/z ratio they are interested in detecting, or a range of m/z ratios at the same time.

Despite the benefits of incorporating mass spectrometry into your analyses, we know MS can seem complex. That is why we designed the Thermo Scientific™ ISQ™ EC single quadrupole mass spectrometer with robustness and ease-of-use in mind. The Thermo Scientific ISQ EC Single Quadrupole Mass Spectrometer enables novices and experts alike to run routine MS and improve analytical confidence by detecting small molecules with high sensitivity in both simple and complex matrices.

The Thermo Scientific™ ISQ™ EC single quadrupole mass spectrometer seamlessly integrates with your ion chromatography (IC) or liquid chromatography (LC) systems. It is robust and easy to use, offering all chromatographers the opportunity to expand their expertise in running routine assays. Its advanced dual-role design provides exceptional low-molecular weight performance for quantitation of ions using IC-MS in addition to reliable, everyday operation for routine LC-MS.


Gain Greater Insights from Your Sample

Coupling ion or liquid chromatography to MS, allows you to gain greater insights from your samples. Adding MS gives you:

  • Higher sensitivity and selectivity
  • Chromatographic peak mass confirmation, reducing the likelihood of false negatives and positives

Resolve Complexity

Confidently analyze samples with complex matrices based on the superior robustness of the ISQ EC mass spectrometers. These single quadrupole mass spectrometers offer:

  • Improved detection of analytes in complex matrices
  • Identification of co-eluting peaks based on their mass-to-charge (m/z) ratios

Easily Master MS

The seamless integration of the ISQ EC mass spectrometers with your IC or LC system allows you to focus on successfully using the system with:

  • Integrated tools to help you quickly learn the MS system
  • Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software for analysis, including embedded control of the mass spectrometer

Providing Innovative Chromatographic Workflow Solutions

Thermo Fisher Scientific offers a comprehensive portfolio of IC and LC instruments to help you solve complex analytical challenges. Our leading-edge workflow solutions—from sample preparation, chromatographic separation, seamless integration with mass spectrometry, and data management and analysis help you meet today’s increasing demands for analytical performance, productivity, and ease-of-use.


The ISQ EC Mass Spectrometer offers:

  • Durable atmospheric pressure ionization (API) source for use with the most challenging sample matrices and innovative vacuum interlock designed for reliable operation
  • High performing HESI-II electrospray to boost ionization effi ciency and spray stability across a wide range of flow rates
  • Built-in reference standard for automated instrument calibration
  • Ultra-fast scanning supports simultaneous analyses of positive and negative ions
  • Easy method development and optimization using new ion source technology
  • Full integration with the Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software
  • Support for open-access LC-MS multi-user applications

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